There is currently no cure for scleroderma however several treatment options exist to mitigate the symptoms of the disease:

• Blood pressure medications that dilate blood vessels may help prevent lung and kidney problems.
• Drugs that suppress the immune system, such as those taken after organ transplants, may help reduce scleroderma symptoms.
• Medications can relieve symptoms of acid reflux.
• Antibiotic ointment, cleaning and protection from the cold may help prevent infection of fingertip ulcers caused by Raynaud's disease.
• Regular influenza and pneumonia vaccinations can help protect lungs that have been damaged by scleroderma.
• If over-the-counter pain relievers don't help enough, you can ask your doctor about stronger medications.

Surgery is a last resort to treat complications from scleroderma.