SJS/TEN is found to have a persisting impact on patients' lives, both physically and psychologically, including many unanswered questions and concerns. Patients are at increased risk of depression and post-traumatic stress disorder following admission to the intensive care unit. Many patients are unable to work following hospital discharge, and others may require modification to their work environment.

Patients are encouraged to speak to their healthcare provider regarding SJS/TEN should they require more education on the disease.